Otx1 function overlaps with Otx2 in development of mouse forebrain and midbrain.

doi:10.1046/j.1365-2443.1996.900288.x

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Article

Otx1 function overlaps with Otx2 in development of mouse forebrain and midbrain.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Nov 1996

Suda Y, Matsuo I, Kuratani S, Aizawa S

Abstract excerpt

BACKGROUND: We previously reported that the homozygous mutation of Otx2 gene, a mouse cognate of the Drosophila head gap gene orthodenticle, causes failure in the development of the rostral head anterior to rhombomere 3, which may correspond to earlier Otx2 expression in cells destined for the an...

Topics

Animals
Base Sequence
Body Patterning
Head
Homeodomain Proteins
Mice
Mutation
Nerve Tissue Proteins
Otx Transcription Factors
Phenotype
Prosencephalon
Trans-Activators
Transcription Factors

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