Article
Kinetic mechanism of a partial folding reaction. 2. Nature of the transition state.
Biochemistry - 24 Feb 1998
Goldberg J M, Baldwin R L
Abstract excerpt
The effects of mutations, temperature, and solvent viscosity on the bimolecular association rate constant (kon) and dissociation rate constant (koff) of the complex (RNaseS*) formed by S-peptide analogues and folded S-protein are reported. An important advantage of this system is that both kon and koff may be measured under identical strongly native conditions, and Kd for the complex may be calculated from the...
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