Article
Conformational plasticity in folding of the split beta-alpha-beta protein S6: evidence for burst-phase disruption of the native state.
Journal of molecular biology - 5 Apr 2002
Otzen Daniel E, Oliveberg Mikael
Abstract excerpt
An increasing number of folding studies of two-state proteins shows that point mutations sometimes change the kinetic m-values, leading to kinks and curves in the chevron plots. The molecular origin of these changes is yet unclear although it is speculated that they are linked to structural rearr...
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