Thermodynamics of denaturation of staphylococcal nuclease mutants: an intermediate state in protein folding.

doi:10.1096/fasebj.10.1.8566550

Back to search

Article

Thermodynamics of denaturation of staphylococcal nuclease mutants: an intermediate state in protein folding.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jan 1996

Carra J H, Privalov P L

Abstract excerpt

A valuable approach to understanding the forces that maintain protein structure is to analyze the thermodynamic effects of mutations on protein folding. The folding process is most often described using an energetic model that assumes a two-state transition between the native and denatured states...

Topics

Micrococcal Nuclease
Models, Chemical
Mutation
Protein Denaturation
Protein Folding
Thermodynamics

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.