Article
Genotyping human arylamine N-acetyltransferase type 1 (NAT1): the identification of two novel allelic variants.
Biochemical pharmacology - 1 Feb 1998
Payton M A, Sim E
Abstract excerpt
Human arylamine N-acetyltransferase (NAT) is known to exist as two isoenzymes, NAT1 and NAT2, with different though overlapping substrate specificities. NAT1 and NAT2 are polymorphic at both genetic and phenotypic levels with four distinct alleles described in Caucasians for NAT1. Though clear genotype/phenotype associations exist for NAT2, the same remains unclear for NAT1. Whole blood taken from 32 individuals...
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