Article
The plasminogen activator system in pancreas cancer: role of t-PA in the invasive potential in vitro.
Oncogene - 5 Feb 1998
Paciucci R, Torà M, Díaz V M, Real F X
Abstract excerpt
Plasminogen activators (PAs) play an important role in tumor cell invasion. We have analysed the expression of tissue-type PA (t-PA), urokinase-type PA (u-PA), and their respective receptors, annexin II and u-PAR, in normal and neoplastic cultures of pancreatic cells, as well as in pancreatic tissues, and have examined their role in tumor invasiveness in vitro. Using Northern blotting, Western blotting, and...
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