Article
Culture conditions modulate cell phenotype and cause selection of subpopulations in PC3 prostate cancer cell line.
Anticancer research - 1 Jan 2000
Festuccia C, Gravina G L, Angelucci A, Millimaggi D, Bologna M
Abstract excerpt
PC3 cell line contains different cell variants. A first variant grows as spherical multicellular aggregates and shows anchorage-independent growth. A second variant grows as single small rounds and shows anchorage-dependent growth without cell spreading. A third variant, representing the most abundant population, grows as adherent cells. These populations differ in alpha 2 beta 1 and alpha 3 beta 1 integrin...
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