Article
PRK1 is targeted to endosomes by the small GTPase, RhoB.
The Journal of biological chemistry - 27 Feb 1998
Mellor H, Flynn P, Nobes C D, Hall A, Parker P J
Abstract excerpt
RhoB has been shown to be an endosomal GTPase both by immunocytochemistry and electron microscopy, however, its role in endocytosis is unknown. Elucidation of the cellular roles of other members of this superfamily of signaling proteins has come with the identification of their downstream partners. We show here that the recently isolated serine/threonine kinase PRK1 is targeted to the endosomal compartment by...
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