Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PRK1 is targeted to endosomes by the small GTPase, RhoB.

The Journal of biological chemistry - 27 Feb 1998

Mellor H, Flynn P, Nobes C D, Hall A, Parker P J

Abstract excerpt

RhoB has been shown to be an endosomal GTPase both by immunocytochemistry and electron microscopy, however, its role in endocytosis is unknown. Elucidation of the cellular roles of other members of this superfamily of signaling proteins has come with the identification of their downstream partner...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Transport
Share to GTP-Binding Proteins
Share to Membrane Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Recombinant Proteins

Share to Sequence Deletion

Share to Signal Transduction

Source

Identifiers

PMID: 9478917
DOI: 10.1074/jbc.273.9.4811

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-9478917-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PRK1 is targeted to endosomes by the small GTPase, RhoB.PMID 9478917Read ↗

Farnesyltransferase inhibitors disrupt EGF receptor traffic through modulation of the RhoB GTPase.Semantic proximity Read ↗

RhoB-dependent modulation of postendocytic traffic in polarized Madin-Darby canine kidney cells.Semantic proximity Read ↗

Molecular dissection of the interaction between the small G proteins Rac1 and RhoA and protein kinase C-related kinase 1 (PRK1).Semantic proximity Read ↗

The very C-terminus of PRK1/PKN is essential for its activation by RhoA and downstream signaling.Semantic proximity Read ↗

The Arf-family protein, Arl8b, is involved in the spatial distribution of lysosomes.Semantic proximity Read ↗

Rab5 is a signalling GTPase involved in actin remodelling by receptor tyrosine kinases.Semantic proximity Read ↗

Regulation of receptor-mediated endocytosis by Rho and Rac.Semantic proximity Read ↗

Isoprenylation of RhoB is necessary for its degradation. A novel determinant in the complex regulation of RhoB expression by the mevalonate pathway.Semantic proximity Read ↗

Dynamics of the subcellular localization of RalBP1/RLIP through the cell cycle: the role of targeting signals and of protein-protein interactions.Semantic proximity Read ↗

Extracellular signal-regulated kinase regulates RhoA activation and tumor cell plasticity by inhibiting guanine exchange factor H1 activity.Semantic proximity Read ↗

Identification of a novel domain of Ras and Rap1 that directs their differential subcellular localizations.Semantic proximity Read ↗

Endosome dynamics regulated by a Rho protein.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.