Article
The Arf-family protein, Arl8b, is involved in the spatial distribution of lysosomes.
Biochemical and biophysical research communications - 16 Jun 2006
Bagshaw Richard D, Callahan John W, Mahuran Don J
Abstract excerpt
Lysosomes are late-endocytic organelles which primarily contribute to degradation and recycling of cellular material. From a previous proteomics study of purified rat liver lysosomal membranes we identified a protein from the Arf-family of small GTPases, Arl8b. Although proteins of the Arf-family have roles in a wide range of cellular functions, most notably roles in protein/vesicular trafficking, Arl8b...
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