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Article

Altered control of cellular proliferation in the absence of mammalian brahma (SNF2alpha).

The EMBO journal - 1 Dec 1998

Reyes J C, Barra J, Muchardt C, Camus A, Babinet C, Yaniv M

Abstract excerpt

The mammalian SWI-SNF complex is an evolutionarily conserved, multi-subunit machine, involved in chromatin remodelling during transcriptional activation. Within this complex, the BRM (SNF2alpha) and BRG1 (SNF2beta) proteins are mutually exclusive subunits that are believed to affect nucleosomal structures using the energy of ATP hydrolysis. In order to characterize possible differences in the function of BRM and...

Topics

Animals
Apoptosis
Cell Division
DNA Damage
DNA Helicases
DNA-Binding Proteins
G1 Phase
Gene Expression Regulation
Mice
Mice, Knockout
Nuclear Proteins
Phenotype

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Up-Regulation

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Identifiers

PMID: 9843504
DOI: 10.1093/emboj/17.23.6979
PMCID: PMC1171046

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-9843504-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Altered control of cellular proliferation in the absence of mammalian brahma (SNF2alpha).PMID 9843504Read ↗

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Combined gene dosage requirement for SWI/SNF catalytic subunits during early mammalian development.Semantic proximity Read ↗

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Casein kinase 2-mediated phosphorylation of Brahma-related gene 1 controls myoblast proliferation and contributes to SWI/SNF complex composition.Semantic proximity Read ↗

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