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Article

Altered control of cellular proliferation in the absence of mammalian brahma (SNF2alpha).

The EMBO journal - 1 Dec 1998

Reyes J C, Barra J, Muchardt C, Camus A, Babinet C, Yaniv M

Abstract excerpt

The mammalian SWI-SNF complex is an evolutionarily conserved, multi-subunit machine, involved in chromatin remodelling during transcriptional activation. Within this complex, the BRM (SNF2alpha) and BRG1 (SNF2beta) proteins are mutually exclusive subunits that are believed to affect nucleosomal structures using the energy of ATP hydrolysis. In order to characterize possible differences in the function of BRM and...

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Identifiers

PMID: 9843504
DOI: 10.1093/emboj/17.23.6979
PMCID: PMC1171046

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Altered control of cellular proliferation in the absence of mammalian brahma (SNF2alpha).PMID 9843504Read ↗

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A Brg1 mutation that uncouples ATPase activity from chromatin remodeling reveals an essential role for SWI/SNF-related complexes in beta-globin expression and erythroid development.Semantic proximity Read ↗

Loss of the SWI/SNF ATPase subunits BRM and BRG1 drives lung cancer developmentSemantic proximity Read ↗

The BRG1 ATPase of Human SWI/SNF Chromatin Remodeling Enzymes as a Driver of CancerSemantic proximity Read ↗

Involvement of the chromatin-remodeling factor BRG1/SMARCA4 in human cancer.Semantic proximity Read ↗

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Casein kinase 2-mediated phosphorylation of Brahma-related gene 1 controls myoblast proliferation and contributes to SWI/SNF complex composition.Semantic proximity Read ↗

Characterization of a Brg1 hypomorphic allele demonstrates that genetic and biochemical activity are tightly correlated.Semantic proximity Read ↗

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