Article
Osmoregulatory transporter ProP influences colonization of the urinary tract by Escherichia coli.
Microbiology (Reading, England) - 1 Jan 1998
Culham Doreen E, Dalgado Cheryl, Gyles Carlton L, Mamelak Daniel, MacLellan Shawn, Wood Janet M
Abstract excerpt
Osmoregulatory transporters ProP and ProU mediate the use of betaines as osmoprotectants by Escherichia coli. Glycine betaine and proline betaine are present in mammalian urines. Betaine uptake may therefore facilitate the growth of E. coli in the urinary tract, an environment of fluctuating osmolality. ProP transporter activity was approximately threefold higher in a pyelonephritis isolate, E. coli HU734, than...
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