Article
ProQ is an RNA chaperone that controls ProP levels in Escherichia coli.
Biochemistry - 19 Apr 2011
Chaulk Steven G, Smith Frieday Michelle N, Arthur David C, Culham Doreen E, Edwards Ross A, Soo Patrick, Frost Laura S, Keates Robert A B, Glover J N Mark, Wood Janet M
Abstract excerpt
Transporter ProP mediates osmolyte accumulation in Escherichia coli cells exposed to high osmolality media. The cytoplasmic ProQ protein amplifies ProP activity by an unknown mechanism. The N- and C-terminal domains of ProQ are predicted to be structurally similar to known RNA chaperone proteins FinO and Hfq from E. coli. Here we demonstrate that ProQ is an RNA chaperone, binding RNA and facilitating both RNA...
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