Article
OmpR regulation of the uropathogenic Escherichia coli fimB gene in an acidic/high osmolality environment
23 Nov 2012
Abstract excerpt
Uropathogenic Escherichia coli (UPEC) causes more than 90 % of all human urinary tract infections through type 1 piliated UPEC cells binding to bladder epithelial cells. The FimB and FimE site-specific recombinases orient the fimS element containing the fimA structural gene promoter. Regulation of fimB and fimE depends on environmental pH and osmolality. The EnvZ/OmpR two-component system affects osmoregulation...
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