Article
Growth of Escherichia coli in human urine: role of salt tolerance and accumulation of glycine betaine.
The Journal of infectious diseases - 1 Dec 1992
Kunin C M, Hua T H, Van Arsdale White L, Villarejo M
Abstract excerpt
Glycine betaine is a powerful osmoprotectant molecule present in the inner medulla of the kidney and excreted into urine. It may be responsible for the ability of Escherichia coli to grow in hypertonic urine. Also, strains of E. coli that cause urinary tract infections may be more salt-tolerant than strains from other sites. To explore these questions, 301 isolates from blood, urine, or stool and 12...
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