Article
An allelotype of papillary thyroid cancer.
International journal of cancer - 20 Dec 1996
Califano J A, Johns M M, Westra W H, Lango M N, Eisele D, Saji M, Zeiger M A, Udelsman R, Koch W M, Sidransky D
Abstract excerpt
Although papillary carcinoma accounts for approximately 70% of all thyroid cancers, preliminary studies of allelic loss have thus far not identified any areas of chromosomal deletion. We evaluated 30 papillary thyroid carcinomas for chromosomal loss/allelic imbalance by testing at least 2 microsatellite markers from every autosomal arm. Fifteen of the 30 tumors tested exhibited loss of heterozygosity/allelic...
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