Allelotype of follicular thyroid carcinomas reveals genetic instability consistent with frequent nondisjunctional chromosomal loss.

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Article

Allelotype of follicular thyroid carcinomas reveals genetic instability consistent with frequent nondisjunctional chromosomal loss.

Genes, chromosomes & cancer - 1 May 1997

Tung W S, Shevlin D W, Kaleem Z, Tribune D J, Wells S A, Goodfellow P J

Abstract excerpt

Numerous studies aimed at the identification of chromosomal regions that are frequently deleted in specific tumor types have pointed to the location and involvement of specific tumor suppressor genes. Previous studies of loss of heterozygosity (LOH) among thyroid tumors have revealed frequent all...

Topics

Adenocarcinoma, Follicular
Alleles
Chromosome Deletion
DNA, Neoplasm
Heterozygote
Humans
Microsatellite Repeats
Nondisjunction, Genetic
Polymerase Chain Reaction
Thyroid Neoplasms

Source

Open in PubMed

Identifiers

PMID: 9135994

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9135994-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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