Article
Allelotype of follicular thyroid carcinomas reveals genetic instability consistent with frequent nondisjunctional chromosomal loss.
Genes, chromosomes & cancer - 1 May 1997
Tung W S, Shevlin D W, Kaleem Z, Tribune D J, Wells S A, Goodfellow P J
Abstract excerpt
Numerous studies aimed at the identification of chromosomal regions that are frequently deleted in specific tumor types have pointed to the location and involvement of specific tumor suppressor genes. Previous studies of loss of heterozygosity (LOH) among thyroid tumors have revealed frequent allelic deletions at a few chromosomal regions. A systematic genome-wide examination of LOH in a substantial number of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
