Article
Allelotyping of follicular thyroid tumors.
Human genetics - 1 Jul 1995
Zedenius J, Wallin G, Svensson A, Grimelius L, Höög A, Lundell G, Bäckdahl M, Larsson C
Abstract excerpt
To elucidate further the genetic mechanisms for follicular thyroid tumor development and progression, we allelotyped follicular thyroid tumors and other thyroid lesions from 92 patients. In general, a low frequency of loss of heterozygosity (LOH) was found, the highest being for chromosomes 3q, 10q, 11p, 11q, 13q, and 22q (10%-15%). However, detailed study of LOH of these chromosome arms with regard to the...
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