Article
Allelotyping of follicular thyroid tumors.
Human genetics - 1 Jul 1995
Zedenius J, Wallin G, Svensson A, Grimelius L, Höög A, Lundell G, Bäckdahl M, Larsson C
Abstract excerpt
To elucidate further the genetic mechanisms for follicular thyroid tumor development and progression, we allelotyped follicular thyroid tumors and other thyroid lesions from 92 patients. In general, a low frequency of loss of heterozygosity (LOH) was found, the highest being for chromosomes 3q, 1...
Topics
- Adenocarcinoma, Follicular
- Alleles
- Chromosome Deletion
- Chromosomes, Human
- DNA, Neoplasm
- DNA, Satellite
- Genes, Tumor Suppressor
- Heterozygote
- Humans
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Repetitive Sequences, Nucleic Acid
- Thyroid Neoplasms