Article
Kindling and associated mossy fibre sprouting are not affected in mice deficient of NGFI-A/NGFI-B genes.
Neuroscience - 1 Mar 1998
Zheng D, Butler L S, McNamara J O
Abstract excerpt
Kindling is an animal model of epileptogenesis, whereby repeated administration of an initially subconvulsive electrical stimulation eventually leads to the development of generalized motor seizures. Once established, the kindling effect is permanent. Although the molecular basis of kindling remains incompletely understood, emerging lines of evidence suggest that the induction of immediate-early genes could...
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