Article
Fyn tyrosine kinase is required for normal amygdala kindling.
Epilepsy research - 1 Oct 1995
Cain D P, Grant S G, Saucier D, Hargreaves E L, Kandel E R
Abstract excerpt
To identify specific genes involved with epileptogenesis kindling was examined in mice carrying mutations engineered by gene targeting. Amygdala kindling was tested in mice with a null-mutation in the Fyn tyrosine kinase gene, a mutation that raises the threshold for the induction of long-term po...
Topics
- Amygdala
- Animals
- Behavior, Animal
- Cells, Cultured
- Epilepsy
- Female
- Kindling, Neurologic
- Male
- Mice
- Mice, Inbred Strains
- Mice, Mutant Strains
- Mutation
- Protein-Tyrosine Kinases