Article
Arylhydrocarbonhydroxylase inducibility and smoking habits in patients with laryngeal carcinomas.
Acta oto-laryngologica - 1 Jan 2000
Korsgaard R, Trell E, Kitzing P, Hood B, Nordén G, Simonsson B, Stiksa G
Abstract excerpt
There is considerable evidence that the inducible enzyme aryl hydrocarbon hydroxylase (AHH) plays an important role in the activation of polycyclic aromatic hydrocarbons (PAH) to ultimate carcinogens. In man, a genetic heterogeneity of AHH inducibility has been demonstrated, and correlated to susceptibility to bronchogenic carcinomas following exposure to PAH. We assessed AHH inducibility in a control group of...
Topics
- Aged
- Aryl Hydrocarbon Hydroxylases
- Enzyme Induction
- Female
- Humans
- Laryngeal Neoplasms
- Male
- Phenotype
- Polycyclic Compounds
- Smoking
