Article
Evidence for linkage between the development of asthma in childhood and the T-cell receptor beta chain gene in Japanese.
Genomics - 1 Jan 1998
Noguchi E, Shibasaki M, Arinami T, Takeda K, Kobayashi K, Matsui A, Hamaguchi H
Abstract excerpt
Susceptibility to the development of asthma and other atopic diseases is known to be associated with genetic components, and several candidate genes have been reported to be linked to atopy and asthma. We have examined a linkage between traits of specific IgE responses to the house dust mite and its purified allergens, high total serum IgE levels and asthma, and the markers at the T-cell receptor (TCR) alpha...
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