Article
Evidence of a strong, positive association between atopy and the HLA class II alleles DR4 and DR7.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Jul 1996
Aron Y, Desmazes-Dufeu N, Matran R, Polla B S, Dusser D, Lockhart A, Swierczewski E
Abstract excerpt
BACKGROUND: Atopy, with or without associated asthma, provides a useful model for evaluating the genetic factors that control human immune responsiveness. HLA class II gene products are involved in the control of immune responses. OBJECTIVES: We investigated whether susceptibility or resistance to the disease was associated with HLA class II genes. METHODS: Blood samples were obtained from two groups of unrelated...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.