Article
Genetic linkage of T-cell receptor alpha/delta complex to specific IgE responses.
Lancet (London, England) - 25 Jun 1994
Moffatt M F, Hill M R, Cornélis F, Schou C, Faux J A, Young R P, James A L, Ryan G, le Souef P, Musk A W
Abstract excerpt
IgE responses to inhaled proteins underlie the clinical syndrome of allergic (atopic) asthma and rhinitis. We have investigated genetic linkage between specific IgE reactions to highly purified major allergens and the T-cell receptor (TCR) alpha and beta gene complexes on chromosome 14 and 7, res...
Topics
- Alleles
- Allergens
- Chromosomes, Human, Pair 14
- Chromosomes, Human, Pair 7
- DNA
- DNA, Satellite
- Genetic Linkage
- Humans
- Hypersensitivity, Immediate
- Immunoglobulin E
- Phenotype
- Receptors, Antigen, T-Cell, alpha-beta