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Article

Use of generalized linear mixed models in analyzing mutant frequency data from the transgenic mouse assay.

Environmental and molecular mutagenesis - 1 Jan 1998

Fung K Y, Lin X, Krewski D

Abstract excerpt

The transgenic mouse assay is now widely used for the study of mutagenesis in diverse rodent tissues and to test chemicals for genotoxic potential. This kind of assay generally involves nested observations at several levels of sampling, e.g., animals, packaging reactions, and plates. Due to the common origin, the mutant frequency (MF) in tissues from the same animal are likely to be positively correlated,...

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Identifiers

PMID: 9464315
DOI: 10.1002/(sici)1098-2280(1998)31:1<48::aid-em7>3.0.co;2-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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