Article
Cocaine, ethanol, and genotype effects on human midbrain serotonin transporter binding sites and mRNA levels.
The American journal of psychiatry - 1 Feb 1998
Little K Y, McLaughlin D P, Zhang L, Livermore C S, Dalack G W, McFinton P R, DelProposto Z S, Hill E, Cassin B J, Watson S J, Cook E H
Abstract excerpt
OBJECTIVE: Earlier platelet and postmortem brain studies have found alterations in serotonin transporter function in ethanol-abusing human subjects. The present investigation tested the hypothesis that brain serotonin transporter function is altered in chronic users of ethanol and cocaine, which might be related to a common serotonin transporter promoter polymorphism. METHOD: Serotonin transporter binding sites,...
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