Article
Generating consistent genotypic configurations for multi-allelic loci and large complex pedigrees.
Human heredity - 1 Jan 2000
Heath S C
Abstract excerpt
Markov chain Monte Carlo techniques have been applied to many different genetic analysis problems. Gibbs sampling in particular has been widely used because of its simplicity and because it can be extended to arbitrarily complex pedigrees and genetic models (albeit with modifications for multi-allelic loci). Gibbs sampling requires an initial genotypic configuration, consistent with observed data, the generation...
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