Article
Irreducibility and efficiency of ESIP to sample marker genotypes in large pedigrees with loops.
Genetics, selection, evolution : GSE - 1 Jan 2000
Fernández Soledad A, Fernando Rohan L, Guldbrandtsen Bernt, Stricker Christian, Schelling Matthias, Carriquiry Alicia L
Abstract excerpt
Markov chain Monte Carlo (MCMC) methods have been proposed to overcome computational problems in linkage and segregation analyses. This approach involves sampling genotypes at the marker and trait loci. Among MCMC methods, scalar-Gibbs is the easiest to implement, and it is used in genetics. However, the Markov chain that corresponds to scalar-Gibbs may not be irreducible when the marker locus has more than two...
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