Article
Oleic Acid Uptake Reveals the Rescued Enterocyte Phenotype of Colon Cancer Caco-2 by HT29-MTX Cells in Co-Culture Mode.
International journal of molecular sciences - 20 Jul 2017
Berger Emmanuelle, Nassra Merian, Atgié Claude, Plaisancié Pascale, Géloën Alain
Abstract excerpt
Gastrointestinal epithelium is the unique route for nutrients and for many pharmaceuticals to enter the body. The present study aimed to analyze precisely whether co-culture of two colon cancer cell lines, mucus-producing cells HT29-MTX and enterocyte-like Caco-2 cells, ameliorate differentiation into an in vitro intestinal barrier model and the signaling pathways involved. Differentiated Caco-2 cells gene...
Topics
- Caco-2 Cells
- Cell Differentiation
- Cell Line, Tumor
- Cell Proliferation
- Coculture Techniques
- Colonic Neoplasms
- Databases, Genetic
- Enterocytes
- Gene Expression Profiling
- Gene Expression Regulation, Neoplastic
- HT29 Cells
- Humans
- Intestinal Mucosa
- Oleic Acid