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Article

Genomic semi-automated cycle sequencing as a sensitive screening technique for p53 mutations in frozen tumor samples.

Oncology reports - 1 Jan 2000

Wang-Gohrke S, Hees S, Pochon A, Wen W H, Reles A, Press M F, Kreienberg R, Runnebaum I B

Abstract excerpt

Single-strand conformational polymorphism (SSCP) is the most widely used method for p53 gene mutation screening. Nucleotide sequence analysis is considered more sensitive for detection of mutations. We established a genomic semi-automated cycle sequencing protocol suitable for p53 gene mutation s...

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Share to Amino Acid Substitution
Share to Genes, p53
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Point Mutation

Share to Polymerase Chain Reaction

Share to Polymorphism, Single-Stranded Conformational

Share to Sensitivity and Specificity

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 9458295
DOI: 10.3892/or.5.1.65

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-9458295-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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