Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Increased hepatic iron concentration in nonalcoholic steatohepatitis is associated with increased fibrosis.

Gastroenterology - 1 Feb 1998

George D K, Goldwurm S, MacDonald G A, Cowley L L, Walker N I, Ward P J, Jazwinska E C, Powell L W

Abstract excerpt

BACKGROUND & AIMS: Nonalcoholic steatohepatitis (NASH) is a chronic liver disease that occasionally progresses to cirrhosis but usually has a benign course. The aim of this study was to investigate the role of the hemochromatosis mutation Cys282Tyr in development of the mild hepatic iron overload found in some patients with NASH and its association with hepatic damage in these patients. METHODS: Fifty-one...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Disease
Share to Cohort Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Markers

Share to Heterozygote

Share to Homozygote

Share to Liver Cirrhosis

Share to Mutation

Share to Sex Factors

Source

Identifiers

PMID: 9453491
DOI: 10.1016/s0016-5085(98)70482-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Increased hepatic iron concentration in nonalcoholic steatohepatitis is associated with increased fibrosis.PMID 9453491Read ↗

HFE mutations, hepatic iron, and fibrosis: ethnic-specific association of NASH with C282Y but not with fibrotic severity.Semantic proximity Read ↗

Non-alcoholic steatohepatitis and iron: increased prevalence of mutations of the HFE gene in non-alcoholic steatohepatitis.Semantic proximity Read ↗

Differences in hepatic phenotype between hemochromatosis patients with HFE C282Y homozygosity and other HFE genotypes.Semantic proximity Read ↗

Lower serum hepcidin and greater parenchymal iron in nonalcoholic fatty liver disease patients with C282Y HFE mutations.Semantic proximity Read ↗

The effect of the metabolic syndrome, hepatic steatosis and steatohepatitis on liver fibrosis in hereditary hemochromatosis.Semantic proximity Read ↗

HFE C282Y mutations are associated with advanced hepatic fibrosis in Caucasians with nonalcoholic steatohepatitis.Semantic proximity Read ↗

Heterozygosity for the hemochromatosis gene in liver diseases--prevalence and effects on liver histology.Semantic proximity Read ↗

Hepatic iron overload in alcoholic end-stage liver disease is associated with iron deposition in other organs in the absence of HFE-1 hemochromatosis.Semantic proximity Read ↗

HFE C282Y heterozygosity in hepatocellular carcinoma: evidence for an increased prevalence.Semantic proximity Read ↗

HFE genotype, parenchymal iron accumulation, and liver fibrosis in patients with nonalcoholic fatty liver disease.Semantic proximity Read ↗

Prevalence of the hemochromatosis gene mutation in patients with nonalcoholic steatohepatitis and correlation with degree of liver fibrosis.Semantic proximity Read ↗

Hfe mutations and iron overload in patients with alcoholic liver disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.