Article
Hfe mutations and iron overload in patients with alcoholic liver disease.
Arquivos de gastroenterologia - 1 Jan 2000
Costa-Matos Luís, Batista Paulo, Monteiro Nuno, Henriques Pedro, Girão Fernando, Carvalho Armando
Abstract excerpt
CONTEXT: Alcoholic liver disease (ALD) is generally associated with iron overload, which may contribute to its pathogenesis, through increased oxidative stress and cellular damage. There are conflicting reports in literature about hemochromatosis (HFE) gene mutations and the severity of liver disease in alcoholic patients. OBJECTIVES: To compare the prevalence of mutations in the hemochromatosis (HFE) gene...
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