Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evidence for expressional crosstalk between the central virulence regulator PrfA and the stress response mediator ClpC in Listeria monocytogenes.

FEMS microbiology letters - 1 Jan 1998

Ripio M T, Vázquez-Boland J A, Vega Y, Nair S, Berche P

Abstract excerpt

Virulence is a multifactorial trait which depends on the coordinated expression of many bacterial products, hence it is to be expected that the regulatory circuits that control the relevant genetic determinants are somehow interconnected. Two pleiotropic regulatory elements acting at different levels, the transcription factor PrfA which controls virulence gene expression and the potential chaperone ClpC which is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Gene Expression Regulation, Bacterial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to RNA, Bacterial

Share to RNA, Messenger

Share to Trans-Activators

Share to Transcription, Genetic

Share to Virulence

Source

Identifiers

PMID: 9453154
DOI: 10.1111/j.1574-6968.1998.tb12798.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence for expressional crosstalk between the central virulence regulator PrfA and the stress response mediator ClpC in Listeria monocytogenes.PMID 9453154Read ↗

Transcriptome analysis of Listeria monocytogenes identifies three groups of genes differently regulated by PrfA.Semantic proximity Read ↗

A naturally occurring mutation K220T in the pleiotropic activator PrfA of Listeria monocytogenes results in a loss of virulence due to decreasing DNA-binding affinity.Semantic proximity Read ↗

A novel mutation within the central Listeria monocytogenes regulator PrfA that results in constitutive expression of virulence gene products.Semantic proximity Read ↗

Functional impact of mutational activation on the Listeria monocytogenes central virulence regulator PrfA.Semantic proximity Read ↗

Negative regulation of PrfA, the key activator of Listeria monocytogenes virulence gene expression, is dispensable for bacterial pathogenesis.Semantic proximity Read ↗

Regulation of the prfA transcriptional activator of Listeria monocytogenes: multiple promoter elements contribute to intracellular growth and cell-to-cell spread.Semantic proximity Read ↗

A Novel Growth-Based Selection Strategy Identifies New Constitutively Active Variants of the Major Virulence Regulator PrfA in Listeria monocytogenes.Semantic proximity Read ↗

The mutation G145S in PrfA, a key virulence regulator of Listeria monocytogenes, increases DNA-binding affinity by stabilizing the HTH motif.Semantic proximity Read ↗

Identification of a ClpC ATPase required for stress tolerance and in vivo survival of Listeria monocytogenes.Semantic proximity Read ↗

Probing the role of protein surface charge in the activation of PrfA, the central regulator of Listeria monocytogenes pathogenesis.Semantic proximity Read ↗

The virulence regulator PrfA promotes biofilm formation by Listeria monocytogenes.Semantic proximity Read ↗

A novel C-terminal mutation resulting in constitutive activation of the Listeria monocytogenes central virulence regulatory factor PrfA.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.