The virulence regulator PrfA promotes biofilm formation by Listeria monocytogenes.

doi:10.1128/JB.00179-10

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Article

The virulence regulator PrfA promotes biofilm formation by Listeria monocytogenes.

Journal of bacteriology - 1 Aug 2010

Lemon Katherine P, Freitag Nancy E, Kolter Roberto

Abstract excerpt

Listeria monocytogenes is a food-borne facultative intracellular pathogen. It is widespread in the environment and has several distinct life-styles. The key transcriptional activator PrfA positively regulates L. monocytogenes virulence genes to mediate the transition from extracellular, flagellum-propelled cell to intracellular pathogen. Here we report the first evidence that PrfA also has a significant positive...

Topics

Bacterial Adhesion
Bacterial Proteins
Biofilms
Gene Expression Regulation, Bacterial
Listeria monocytogenes
Mutation
Peptide Termination Factors
Temperature

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Identifiers

PMID: 20511507
DOI: 10.1128/JB.00179-10
PMCID: PMC2916369

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