Article
Identification of a ClpC ATPase required for stress tolerance and in vivo survival of Listeria monocytogenes.
Molecular microbiology - 1 Sept 1996
Rouquette C, Ripio M T, Pellegrini E, Bolla J M, Tascon R I, Vázquez-Boland J A, Berche P
Abstract excerpt
We identified a new chromosomal locus involved in the virulence of the facultative intracellular pathogen Listeria monocytogenes. This locus displays the same genetic organization as that of the clpC/mecB locus of Bacillus subtilis. It contains a thermoregulated operon of four genes, whose transc...
Topics
- Adenosine Triphosphatases
- Amino Acid Sequence
- Animals
- Bacterial Proteins
- Cloning, Molecular
- Female
- Gene Expression Regulation, Bacterial
- Heat-Shock Proteins
- Iron
- Listeria monocytogenes
- Macrophages
- Mice
- Mice, Inbred C57BL
- Mice, Inbred ICR
- Molecular Sequence Data
- Phenotype
- Restriction Mapping
- Sequence Analysis, DNA