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Article

Identification and characterization of Escherichia coli DNA helicase II mutants that exhibit increased unwinding efficiency.

Journal of bacteriology - 1 Jan 1998

Zhang G, Deng E, Baugh L, Kushner S R

Abstract excerpt

Using a combination of both ethyl methanesulfonate and site-directed mutagenesis, we have identified a region in DNA helicase II (UvrD) from Escherichia coli that is required for biological function but lies outside of any of the seven conserved motifs (T. C. Hodgman, Nature 333:22-23, 1988) associated with the superfamily of proteins of which it is a member. Located between amino acids 403 and 409, alterations...

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Identifiers

PMID: 9440527
DOI: 10.1128/JB.180.2.377-387.1998
PMCID: PMC106893

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