Identification and characterization of Escherichia coli DNA helicase II mutants that exhibit increased unwinding efficiency.

doi:10.1128/JB.180.2.377-387.1998

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Article

Identification and characterization of Escherichia coli DNA helicase II mutants that exhibit increased unwinding efficiency.

Journal of bacteriology - 1 Jan 1998

Zhang G, Deng E, Baugh L, Kushner S R

Abstract excerpt

Using a combination of both ethyl methanesulfonate and site-directed mutagenesis, we have identified a region in DNA helicase II (UvrD) from Escherichia coli that is required for biological function but lies outside of any of the seven conserved motifs (T. C. Hodgman, Nature 333:22-23, 1988) asso...

Topics

Adenosine Triphosphatases
DNA Helicases
DNA Topoisomerases, Type I
Escherichia coli
Escherichia coli Proteins
Methyl Methanesulfonate
Mutation
Recombination, Genetic
Temperature

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