Article
Genetic analysis of the CYP2D6 gene in patients with Parkinson's disease.
Metabolism: clinical and experimental - 1 Jan 1998
Tsuneoka Y, Matsuo Y, Ichikawa Y, Watanabe Y
Abstract excerpt
To further investigate the association between Parkinson's disease (PD) and genetic polymorphism of the CYP2D6 gene, a mutant allele (CVP2D6J) frequently observed in the Japanese population and related to EM/PM polymorphism (phenotypically, individuals are either extensive metabolizers [EM] or poor metabolizers [PM] of debrisoquine) was investigated. The CYP2D6J gene with a nucleotide substitution from C to T at...
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