Genetic polymorphism of cytochrome P450 2D6 in idiopathic Parkinson disease and diffuse Lewy body disease.

doi:10.1097/00002826-199410000-00014

Back to search

Article

Genetic polymorphism of cytochrome P450 2D6 in idiopathic Parkinson disease and diffuse Lewy body disease.

Clinical neuropharmacology - 1 Oct 1994

Bordet R, Broly F, Destee A, Libersa C

Abstract excerpt

We investigated genetic polymorphism of the cytochrome P450 CYP 2D6 gene in 105 caucasian patients with idiopathic Parkinson's disease (IPD) and 15 patients with diffuse Lewy body disease (DLBD). The mutations of the CYP 2D6 gene associated with the poor metabolizer (PM) phenotype of the debrisoq...

Topics

Aged
Cytochrome P-450 CYP2D6
Female
Genotype
Humans
Male
Middle Aged
Mutation
Parkinson Disease
Polymerase Chain Reaction
Polymorphism, Genetic

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.