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Article

A novel cytochrome P-450IID6 mutant gene associated with Parkinson's disease.

Journal of biochemistry - 1 Aug 1993

Tsuneoka Y, Matsuo Y, Iwahashi K, Takeuchi H, Ichikawa Y

Abstract excerpt

Genetic polymorphism of the CYP2D6 gene [phenotypically individuals are either poor metabolizers (PM) or extensive metabolizers (EM)] has been reported to be associated with susceptibility to Parkinson's disease. We analyzed CYP2D6 genes from Japanese patients and controls, and found that EM/PM polymorphism is not a suitable marker for populations with a low PM frequency. However, a novel mutant highly associated...

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Identifiers

PMID: 7903297
DOI: 10.1093/oxfordjournals.jbchem.a124164

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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