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Article

Efficacy of taxol in the orpk mouse model of polycystic kidney disease.

Pediatric nephrology (Berlin, Germany) - 1 Dec 1997

Sommardahl C S, Woychik R P, Sweeney W E, Avner E D, Wilkinson J E

Abstract excerpt

Polycystic kidney disease (PKD) a is common disease in the human population that can lead to renal failure and death. Taxol has recently been reported to be of therapeutic benefit in the cpk mouse model of PKD. To determine whether these results also apply to other models of PKD, we studied the effects of taxol treatment on the development of renal cysts and biliary hyperplasia/dysplasia/fibrosis in the orpk...

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PMID: 9438653
DOI: 10.1007/s004670050376

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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