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Article

Fish mesonephric model of polycystic kidney disease in medaka (Oryzias latipes) pc mutant.

Kidney international - 1 Jul 2005

Mochizuki Emiko, Fukuta Katsuhiro, Tada Tatsuya, Harada Tomohiro, Watanabe Naoki, Matsuo Seiichi, Hashimoto Hisashi, Ozato Kenjiro, Wakamatsu Yuko

Abstract excerpt

BACKGROUND: Polycystic kidney disease (PKD) is a common hereditary disease. A number of murine and zebrafish mutants have been generated and used for the study of PKD as metanephric and pronephric models, respectively. Here, we report a medaka (Oryzias latipes) mutant that develops numerous cysts in the kidney in adulthood fish in an autosomal-recessive manner as a mesonephric model of PKD. METHODS: The...

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PMID: 15954893
DOI: 10.1111/j.1523-1755.2005.00378.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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