Heavy-chain variable regions in carcharhine sharks: development of a comprehensive model for the evolution of VH domains among the gnathanstomes.

doi:10.1038/icb.1996.63

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Heavy-chain variable regions in carcharhine sharks: development of a comprehensive model for the evolution of VH domains among the gnathanstomes.

Immunology and cell biology - 1 Aug 1996

Shen S X, Bernstein R M, Schluter S F, Marchalonis J J

Abstract excerpt

We determined the sequence of 18 DNA clones encoding VH regions of sandbar shark and bull shark. All of these sequences exhibit key structural coding features characteristic of known VH genes of higher vertebrates. These VH sequences disclosed considerable diversity, and can be divided into six f...

Topics

Amino Acid Sequence
Animals
Base Sequence
DNA, Complementary
Evolution, Molecular
Genetic Variation
Immunoglobulin Heavy Chains
Immunoglobulin Variable Region
Models, Immunological
Molecular Sequence Data
Phylogeny
Sequence Homology, Amino Acid
Sharks

Source

Open in PubMed

Identifiers

PMID: 8872187
DOI: 10.1038/icb.1996.63

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8872187-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics