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Article

Epidermal growth factor-induced activation and translocation of c-Src to the cytoskeleton depends on the actin binding domain of the EGF-receptor.

Biochimica et biophysica acta - 12 Dec 1997

Van der Heyden M A, Oude Weernink P A, Van Oirschot B A, Van Bergen en Henegouwen P M, Boonstra J, Rijksen G

Abstract excerpt

In the epidermal growth factor (EGF)-receptor signal transduction cascade, the non-receptor tyrosine kinase c-Src has been demonstrated to become activated upon EGF stimulation. In this paper we show that c-Src associates with the cytoskeleton and co-isolates with actin filaments upon EGF treatme...

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Source

Identifiers

PMID: 9434127
DOI: 10.1016/s0167-4889(97)00105-5

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-9434127-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Epidermal growth factor-induced activation and translocation of c-Src to the cytoskeleton depends on the actin binding domain of the EGF-receptor.PMID 9434127Read ↗

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Kinetics of tyrosine phosphorylation and internalization of human EGF receptors overexpressed in NIH 3T3 fibroblasts.Semantic proximity Read ↗

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p130(Cas), an assembling molecule of actin filaments, promotes cell movement, cell migration, and cell spreading in fibroblasts.Semantic proximity Read ↗

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