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Article

A new test statistic for linkage applied to bipolar disorder and marker D18S41.

Genetic epidemiology - 1 Jan 1997

Cleves M A, Dawson D V, Elston R C, Schnell A H

Abstract excerpt

We applied a new test statistic for linkage that removes the traditional assumption of equal female (theta f) and male (theta m) recombination fractions by testing Ho: theta f + theta m = 1 vs. HA: theta f + theta m < 1 to GAW10 Problem 1. Specifically we reanalyzed the reported possible linkage between a suggested susceptibility locus for bipolar affective disorder and marker D18S41 on chromosome 18 [Stine et...

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PMID: 9433546
DOI: 10.1002/(SICI)1098-2272(1997)14:6<581::AID-GEPI5>3.0.CO;2-2

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