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Article

A new test statistic for linkage applied to bipolar disorder and marker D18S41.

Genetic epidemiology - 1 Jan 1997

Cleves M A, Dawson D V, Elston R C, Schnell A H

Abstract excerpt

We applied a new test statistic for linkage that removes the traditional assumption of equal female (theta f) and male (theta m) recombination fractions by testing Ho: theta f + theta m = 1 vs. HA: theta f + theta m < 1 to GAW10 Problem 1. Specifically we reanalyzed the reported possible linkage...

Topics

Alleles
Bipolar Disorder
Chi-Square Distribution
Female
Gene Frequency
Genetic Linkage
Genetic Markers
Humans
Likelihood Functions
Lod Score
Male
Models, Genetic
Models, Statistical

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9433546
DOI: 10.1002/(SICI)1098-2272(1997)14:6<581::AID-GEPI5>3.0.CO;2-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9433546-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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