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Article

Mutational analysis of Csc1/Vps4p: involvement of endosome in regulation of autophagy in yeast.

Cell structure and function - 1 Oct 1997

Shirahama K, Noda T, Ohsumi Y

Abstract excerpt

In the yeast Saccharomyces cerevisiae, autophagy, a bulk protein degradation in the vacuole, is induced in response to nutrient starvation. In a screen for mutations that result in induction of autophagy even in the presence of nutrients, we have isolated four mutants representing two csc complementation groups. These mutants induce autophagy of which activity is represented by activation of truncated alkaline...

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PMID: 9431454
DOI: 10.1247/csf.22.501

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NSF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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