Article
The early secretory pathway contributes to autophagy in yeast.
Cell structure and function - 1 Feb 2003
Hamasaki Maho, Noda Takeshi, Ohsumi Yoshinori
Abstract excerpt
Autophagy is a starvation response in eukaryotes by which the cell delivers cytoplasmic components to the vacuole for degradation, and is mediated by a double membrane structure called the autophagosome. We have previously proposed that the specific combination of COPII like components, including Sec24p, is required for autophagy (Ishihara, N. et al. (2001) Mol. Biol. Cell, 12: 3690-3702). The autophagic defect...
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