Article
Serotonin transporter and seasonal variation in blood serotonin in families with obsessive-compulsive disorder.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Feb 1998
Hanna G L, Himle J A, Curtis G C, Koram D Q, Veenstra-VanderWeele J, Leventhal B L, Cook E H
Abstract excerpt
The serotonin transporter (HTT) is a candidate gene for obsessive-compulsive disorder (OCD) that has been associated with anxiety-related traits. The long (l) and short (s) variants of the HTT promoter have different transcriptional efficiencies. HTT promoter genotype and blood 5-HT concentration were examined in 70 subjects from 20 families ascertained through children and adolescents with a DSM-III-R diagnosis...
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