Article
The Drosophila p38 MAPK pathway is required during oogenesis for egg asymmetric development.
Genes & development - 1 Jun 1999
Suzanne M, Irie K, Glise B, Agnès F, Mori E, Matsumoto K, Noselli S
Abstract excerpt
In mammalian cells, the p38 mitogen-activated protein kinase (MAPK) pathway is activated in response to a variety of environmental stresses and inflammatory stimuli. However, the role of p38 MAPK signaling in unchallenged conditions remains largely unknown. We have isolated mutations in a Drosophila p38 MAPKK gene homolog, licorne (lic), and show that during oogenesis, lic is required in the germ line for correct...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
