Article
Specific phosphatidylethanolamine dependence of Serratia marcescens cytotoxin activity.
Molecular microbiology - 1 Dec 1997
Hertle R, Brutsche S, Groeger W, Hobbie S, Koch W, Könninger U, Braun V
Abstract excerpt
The cytolytic and haemolytic activity of Serratia marcescens is determined by the ShlA protein, which is secreted across the outer membrane with the aid of the ShlB protein. In the absence of ShlB, inactive ShlA* remains in the periplasm of Escherichia col transformed with an shlA-encoding plasmid, which indicates that ShlB converts ShlA* to active ShlA. ShlA* in a periplasmic extract and partially purified ShlA*...
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