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Article

Streptococcus pyogenes cytolysin-mediated translocation does not require pore formation by streptolysin O.

EMBO reports - 1 May 2010

Magassa N'Goundo, Chandrasekaran Sukantha, Caparon Michael G

Abstract excerpt

Bacterial toxin injection into the host cell is required for the virulence of numerous pathogenic bacteria. Cytolysin-mediated translocation (CMT) of Streptococcus pyogenes uses streptolysin O (SLO) to translocate the S. pyogenes nicotinamide adenine dinucleotide-glycohydrolase (SPN) into the hos...

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Identifiers

PMID: 20339385
DOI: 10.1038/embor.2010.37
PMCID: PMC2868537

Genes

SPN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20339385-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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