Article
Secretion and activation of the Serratia marcescens hemolysin by structurally defined ShlB mutants.
International journal of medical microbiology : IJMM - 1 May 2014
Pramanik Avijit, Könninger Ulrich, Selvam Arun, Braun Volkmar
Abstract excerpt
The ShlA hemolysin of Serratia marcescens is secreted across the outer membrane by the ShlB protein; ShlB belongs to the two-partner secretion system (type Vb), a subfamily of the Omp85 outer membrane protein assembly and secretion superfamily. During secretion, ShlA is converted from an inactive non-hemolytic form into an active hemolytic form. The structure of ShlB is predicted to consist of the N-terminal...
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